Mohamadzadeh Lab

 

 

Research Interests

Dr. Mohamadzadeh is an immunologist with over 25 years of expertise in the fields of inflammation, systemic/mucosal immunology, infection, and vaccine delivery. He is also experienced in working with various therapeutic approaches that focus on the role of innate immune cells–particularly dendritic cells, and how these cells determine the activation and differentiation of T lymphocytes, including T cells, such as TH17 or extrathymic regulatory T cells (Tregs) in steady state, during infection, and throughout inflammatory intestinal disorders such as inflammatory bowel disease (IBD) and necrotizing enterocolitis (NEC). In his opinion, understanding the molecular mechanisms underlying intestinal immune regulation is most effective when host interactions with intestinal bacterial species and their bacterial products are fully understood, and when the critical molecules that culminate in inflammation or anti-inflammatory responses are identified. Thus, his research is firmly centered on the specifics of beneficial gut microbes, their unique properties, and their role in the induction of stimulatory or regulatory signals in innate cells and T lymphocytes, contributing directly to further proinflammation or regulation of inflammatory diseases (IBD, NEC). Pragmatically, his research is tightly entwined with generating novel therapies for intestinal disorders (e.g. NEC) using beneficial bacteria such as P. UF1 to significantly regulate induced pathogenic inflammation in sufferers who urgently need it.


 

Personnel

 

Zadeh

Mansour Mohamadzadeh, PhD
Principal Investigator
Professor

 

 

Ge

Yong Ge, PhD
Research Assistant Professor

Roth-William

William Roth, MD
Assistant Professor

 

 

 

 

 

 

 

 

 

 

 

Zadeh

Mojgan Zadeh, MS
Lab Manager

Ni Zhao

Ni Zhao, PhD
Postdoctoral Fellow

 

 

 

 

 

 

 

 

 

 

 

 

 

Rushi

Rushi M. Vekariya
Undergraduate Assistant

grace-liu

Grace Liu
Undergraduate Assistant


Alumni

  • Yaima Lightfoot, PhD

  • Bikash Sahay, PhD

  • Natacha Colliou, PhD

  • Jing Li, PhD

  • Minghao Gong, PhD

  • Jennifer Owen, DVM, PhD